Time from PSC diagnosis to liver transplant

What is known

• The closest related figure is transplant-free survival, reported as a median of 9 to 21 years from diagnosis. ¹
• Symptomatic-patient survival has been estimated at about 12 years from diagnosis. ²

What is unknown / caveats

• The provided excerpts do not report a median interval from PSC diagnosis to liver transplantation.
• Neither of these figures is a diagnosis-to-transplant interval specifically in those who progress to end-stage disease.

References

1. Frolkis AD, Nayagam JS, Parente A, Seager M, Sadler MD, Montano-Loza AJ, Joshi D. Evaluation and management of primary sclerosing cholangitis patients awaiting liver transplantation. JHEP Rep. 2026. PMID: 41825099.

2. Worthington J, Chapman R. Primary sclerosing cholangitis. Orphanet J Rare Dis. 2006. PMID: 17062136.

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Draft, generated by the IBDology RAG and not yet clinician-reviewed. Answers are grounded in the retrieved literature listed above; a high faithfulness score means the answer matches its sources, not that the sources are correct.